eart Rhythm Considerations in Heart Transplant Candidates and onsiderations for Ventricular Assist Devices: International ociety for Heart and Lung Transplantation Guidelines for he Care of Cardiac Transplant

نویسنده

  • Maria Rosa Costanzo
چکیده

egardless of underlying etiology, heart failure may be ssociated with an abnormal sequence of ventricular ontractions, referred to as cardiac or ventricular dysynchrony. This abnormality may be due to both disurbed electrical activation and regional abnormalities n contraction due to ischemia, myocardial scarring or eplacement of myocardium by infiltrative diseases. pproximately 33% of patients with systolic heart failre have evidence of abnormal electrical activation on urface electrocardiogram (ECG), seen as a QRS duraion of 120 milliseconds, most commonly as a left undle branch block (LBBB). The ventricular contracion pattern associated with LBBB results in the followng abnormalities: abnormal ventricular septal motion ith movement paradoxical to the lateral wall of the eft ventricle, and thus a decrease in regional left entricular ejection fraction (LVEF); a delay in mitral alve opening and aortic valve closure resulting in a hortened left ventricular (LV) filling time; and mitral egurgitation, caused or aggravated by dyssynchronous ctivation of papillary muscles and the surrounding yocardium and incomplete closure of the mitral valve aused by late ventricular contraction. In addition to dyssynchrony resulting from underlyng cardiac pathologies, some data suggest that cariac dyssynchrony induced by a pacemaker (right entricular [RV] or combined right atrial [RA] and

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تاریخ انتشار 2006